Antidepressants for Migraine Headaches
Antidepressant medications, which are usually used to treat depression, can be effective in preventing migraine headaches. Antidepressants have some pain-relieving properties and may reduce duration and frequency of headaches. Antidepressants are also used to improve sleep problems.
Other tricyclic antidepressants may be tried if you do not respond well to amitriptyline or nortriptyline. The choice of antidepressant to treat your migraines may depend on your ability to tolerate the side effects of the medication.
Side effects of tricyclic antidepressants include:
- Dry mouth.
- Blurred vision.
- Inability to urinate.
- Weight gain.
- Low blood pressure when you stand up quickly.
The U.S. Food and Drug Administration (FDA) has issued an advisory on antidepressant medicines and the risk of suicide. The FDA does not recommend that people stop using these medicines. Instead, a person taking antidepressants should be watched for warning signs of suicide. This is especially important at the beginning of treatment or when the doses are changed.
|Editor||Kathleen M. Ariss, MS|
|Associate Editor||Michele Cronen|
|Associate Editor||Terrina Vail|
|Primary Medical Reviewer||Martin Gabica, MD - Family Medicine|
|Primary Medical Reviewer||Kathleen Romito, MD - Family Medicine|
|Specialist Medical Reviewer||Colin Chalk, MD, CM, FRCPC - Neurology|
|Last Updated||June 30, 2009|
Last Updated: June 30, 2009