Corticobasal Degeneration

National Organization for Rare Disorders, Inc.

Important
It is possible that the main title of the report Corticobasal Degeneration is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.

Synonyms

  • Cortical-Basal Ganglionic Degeneration
  • Cortico-Basal Ganglionic Degeneration (CBGD)
  • CBGD

Disorder Subdivisions

  • None

General Discussion

Corticobasal degeneration is a rare progressive neurological disorder characterized by cell loss and shrinkage (atrophy) in certain areas of the brain (cerebral cortex and substantia nigra). Affected individuals may have sufficient muscle power for manual tasks but often have difficulty directing their movements appropriately. Initial symptoms typically appear in people during the sixth decade, and may include poor coordination, difficulty accomplishing goal-directed tasks (e.g., buttoning a shirt), and/or difficulty pantomiming actions. Symptoms usually begin on one side of the body (unilateral), but both sides may be affected as the disease progresses. Cognitive impairment (e.g., memory loss) and/or visual-spatial impairments may also occur. The exact cause of corticobasal degeneration is unknown.
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Resources

WE MOVE (Worldwide Education and Awareness for Movement Disorders)
204 West 84th Street
New York, NY 10024
USA
Tel: (212)875-8312
Fax: (212)875-8389
Email: wemove@wemove.org
Internet: http://www.wemove.org

CurePSP: Society for Progressive Supranuclear Palsy
Executive Plaza III
11350 McCormick Road, Suite 906
Hunt Valley, MD 21031
Tel: (410)785-7004
Fax: (410)785-7009
Tel: (800)457-4777
Email: info@curepsp.org
Internet: http://www.psp.org

National Institute of Neurological Disorders and Stroke (NINDS)
P.O. Box 5801
Bethesda, MD 20824
Tel: (301)496-5751
Fax: (301)402-2186
Tel: (800)352-9424
TDD: (301)468-5981
Email: me20t@nih.gov
Internet: http://www.ninds.nih.gov/

Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg, MD 20898-8126
Tel: (301)251-4925
Fax: (301)251-4911
Tel: (888)205-2311
TDD: (888)205-3223
Email: ordr@od.nih.gov
Internet: http://rarediseases.info.nih.gov/Default.aspx

UCSF Memory and Aging Center
350 Parnassus Avenue
Suite 706
San Francisco, CA 94117
Tel: (415)476-6800
Fax: (415)476-4800
Internet: http://memory.ucsf.edu

Association for Frontotemporal Dementias (AFTD)
1616 Walnut Street, Suite 1100
Philadelphia, PA 19103
Tel: (267)514-7221
Tel: (866)507-7222
Email: info@ftd-picks.org
Internet: http://www.ftd-picks.org

For a Complete Report

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ® (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html

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