National Organization for Rare Disorders, Inc.
It is possible that the main title of the report Neonatal Lupus is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
- Congenital Lupus
- Congenital Lupus Erythematosus
- Neonatal Lupus Erythematosus
- Neonatal Lupus Syndrome
Neonatal lupus is a rare autoimmune disorder that is present at birth (congenital). Affected infants often develop a characteristic red rash or skin eruption. In addition, infants with neonatal lupus may develop liver disease, a heart condition known as congenital heart block, and/or low numbers of circulating blood platelets that assist in blood clotting functions (thrombocytopenia). The symptoms associated with neonatal lupus, with the exception of congenital heart block, usually resolve within the first several months of life.
The exact cause of neonatal lupus is unknown, although researchers speculate that specific antibodies that travel from a pregnant woman to her developing fetus via the placenta play a significant role.
Neonatal lupus is not the infant form of lupus (systemic lupus erythematosus) although the skin rash resembles the one associated with lupus. Neonatal lupus is a separate disorder.
March of Dimes Birth Defects Foundation
1275 Mamaroneck Avenue
White Plains, NY 10605
American Autoimmune Related Diseases Association, Inc.
22100 Gratiot Avenue
Eastpointe, MI 48021
Lupus Foundation of America, Inc.
2000 L Street NW
Washington, DC 20036
3555 14th Avenue, Unit #3,
Ontario, L3R 0H5
Tel: (905) 513-0004
Fax: (905) 513-9516
Tel: (800) 661-1468
NIH/National Institute of Child Health and Human Development
31 Center Dr
Building 31, Room 2A32
Bethesda, MD 20892
Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg, MD 20898-8126
Tel: (919) 552-9057
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This is an abstract of a report from the National Organization for Rare Disorders, Inc. ® (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html