Familial Adenomatous Polyposis

National Organization for Rare Disorders, Inc.

It is possible that the main title of the report Familial Adenomatous Polyposis is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.


  • FAP
  • Adenomatous polyposis of the colon (APC)
  • Multiple Polyposis of the Colon
  • Hereditary Polyposis Coli
  • Familial Multiple Polyposis

Disorder Subdivisions

  • Gardner Syndrome
  • Turcot Syndrome
  • familial adenomatous polyposis
  • attenuated FAP

General Discussion

Familial adenomatous polyposis (FAP) is a rare inherited cancer predisposition syndrome characterized by hundreds to thousands of precancerous colorectal polyps (adenomatous polyps). If left untreated, affected individuals inevitably develop cancer of the colon and/or rectum. FAP is inherited in an autosomal dominant manner and caused by abnormalities (mutations) in the APC gene. Mutations in the APC gene cause a group of polyposis conditions that have overlapping features: familial adenomatous polyposis, Gardner syndrome, Turcot syndrome and attenuated FAP.



March of Dimes Birth Defects Foundation
1275 Mamaroneck Avenue
White Plains, NY 10605
Tel: (914)997-4488
Fax: (914)997-4763
Tel: (888)663-4637
Email: Askus@marchofdimes.com
Internet: http://www.marchofdimes.com

Familial GI Cancer Registry
Mt. Sinai Hospital
60 Murray Street, 3rd Floor
ON, M5T 3L9
Tel: (416) 586-4800 ext. 8334
Fax: (416) 586-5924
Email: tberk@mtsinai.on.ca
Internet: http://www.mountsinai.on.ca/care/fgicr

Intestinal Multiple Polyposis and Colorectal Cancer Registry
P.O. Box 11
Conyngham, PA 18219
Tel: (717)788-3712
Fax: (717)788-4046
Email: user291524@aol.com

American Cancer Society, Inc.
1599 Clifton Road NE
Atlanta, GA 30329
Tel: (404)320-3333
Tel: (800)227-2345
TDD: (866)228-4327
Internet: http://www.cancer.org

Familial Polyposis Registry
Department of Colorectal Surgery
Cleveland Clinic Foundation
9500 Euclid Avenue
Cleveland, OH 44195-5001
Tel: (216)444-6470

John Hopkins Colorectal Cancer Screening
600 North Wolfe Street
Baltimore, MD 21287
Tel: (410)955-4166
Internet: http://www.hopkins-gi.org

NIH/National Digestive Diseases Information Clearinghouse
2 Information Way
Bethesda, MD 20892-3570
Tel: (301)654-3810
Fax: (301)907-8906
Tel: (800)891-5389
Email: nddic@info.niddk.nih.gov
Internet: http://www.niddk.nih.gov

National Cancer Institute
6116 Executive Blvd, MSC 8322, Room 3036A
Bethesda, MD 20892-8322
Tel: (301)435-3848
Tel: (800)422-6237
TDD: (800)332-8615
Internet: http://www.cancer.gov

Southeastern Hereditary Colorectal Cancer Registry
University Hospital
1350 Walton Way
Augusta, GA 30910-3599
Tel: (706)774-8900
Fax: (706)774-8915
Email: cwheeler@uh.org

Delaware Cancer Registry
417 Federal Street
Jesse Cooper Building
Dover, DE 19901
Tel: (302)744-4700
Fax: (302)739-6659
Email: cmarker@state.de.us
Internet: http://www.dhss.delaware.gov/dhss/dph/dpc/registry.html

Roswell Park Family Cancer Registry
Elm & Carlton Streets
Buffalo, NY 14263
Tel: (716)845-8400
Fax: (716)845-4556
Tel: (800)685-6825
Email: askrpci@roswellpark.org
Internet: http://www.roswellpark.org

Ferguson Hospital
71 Sheldon Boulevard
Grand Rapids, MI 49503
Tel: (616)456-0202

Northwestern University Medical School
Department of Surgery
233 East Erie Street
Suite 100
Chicago, IL 60611
Tel: (312)943-5427

M. D. Anderson Cancer Center Hereditary Colorectal Cancer Registry
Department of Gastrointestinal Oncology
Box 78, 1515 Holcombe Blvd.
Houston, TX 77030
Tel: (713)792-3245
Fax: (713)745-1163
Tel: (877)632-6789
Email: hcc-editor@mdacc.tmc.edu
Internet: http://www.mdanderson.org/about-us/index.html

OncoLink: The University of Pennsylvania Cancer Center Resource
3400 Spruce Street
2 Donner
Philadelphia, PA 19104-4283
Tel: (215)349-5445
Fax: (215)349-5445
Email: editors@oncolink.upenn.edu
Internet: http://www.oncolink.upenn.edu

Strang-Cornell Hereditary Colon Cancer Program
428 East 72nd Street
New York, NY 10021
Tel: (212)794-4900
Fax: (212)794-4958
Email: mbertagnolli@partners.org
Internet: http://www.strang.org

Rare Cancer Alliance
1649 North Pacana Way
Green Valley, AZ 85614
Tel: (520)625-5495
Fax: (615)526-4921
Email: sharon.lane@rare-cancer.org
Internet: http://www.rare-cancer.org

MUMS National Parent-to-Parent Network
150 Custer Court
Green Bay, WI 54301-1243
Tel: (920)336-5333
Fax: (920)339-0995
Tel: (877)336-5333
Email: mums@netnet.net
Internet: http://www.netnet.net/mums/

Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg, MD 20898-8126
Tel: (301)251-4925
Fax: (301)251-4911
Tel: (888)205-2311
TDD: (888)205-3223
Email: ordr@od.nih.gov
Internet: http://rarediseases.info.nih.gov/Default.aspx

Madisons Foundation
PO Box 241956
Los Angeles, CA 90024
Tel: (310)264-0826
Fax: (310)264-4766
Email: getinfo@madisonsfoundation.org
Internet: http://www.madisonsfoundation.org

Friends of Cancer Research
2231 Crystal Drive
Suite 200
Arlington, VA 22202
Tel: (703)302-1503
Fax: (703)302-1568
Email: info@focr.org
Internet: http://www.focr.org

American Society of Clinical Oncology
2318 Mill Road
Suite 800
Alexandria, VA 22314
Tel: (571)483-1780
Fax: (571)366-9537
Tel: (888)651-3038
Email: contactus@cancer.net
Internet: http://www.cancer.net/patient

Wellness Community
919 18th Street N.W.
Suite 54
Washington, DC 20006
Tel: (202)659-9709
Fax: (202)659-9301
Tel: (888)793-9355
Email: help@thewellnesscommunity.org
Internet: http://www.thewellnesscommunity.org

Desmoid Tumor Research Foundation
P.O. Box 273
Suffern, NY 10901
Tel: (914)262-6595
Fax: (845)369-8302
Email: marlene@dtrf.org
Internet: http://www.dtrf.org

Lance Armstrong Foundation
2201 E. Sixth Street
Austin, TX 78702
Tel: (512)236-8820
Fax: (512)236-8482
Tel: (877)236-8820
Email: media@livestrong.org
Internet: http://www.livestrong.org

3 St. Andrews Place
London, NW1 4LB
Tel: 020 7486 0341
Fax: 020 7224 2012
Email: info@corecharity.org.uk
Internet: http://www.corecharity.org.uk

For a Complete Report

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ® (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html

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