Multiple System Atrophy
National Organization for Rare Disorders, Inc.
It is possible that the main title of the report Multiple System Atrophy is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
- Shy-Drager Syndrome (SDS)
- Sporadic Olivopontocerebellar Atrophy
- Progressive Autonomic Failure with Multiple System Atrophy
- Sporadic OPCA
- Striatonigral Degeneration (SND)
Multiple system atrophy (MSA) is a rare progressive neurological disorder characterized by a varying combination of symptoms. Affected individuals may experience symptoms similar to those found in Parkinson's disease (parkinsonism); cerebellar signs such as progressive impairment of the ability to coordinate voluntary movements (cerebellar ataxia); and impaired functioning of the portion of the nervous system (autonomic nervous system) that regulates certain involuntary body functions (autonomic failure) such as heart rate, blood pressure, sweating, and bowel and bladder control. The exact cause of multiple system atrophy is unknown.
The term multiple system atrophy has generated significant controversy and confusion in the medical literature. The term now encompasses three conditions once thought to be separate disorders, specifically Shy-Drager syndrome, striatonigral degeneration, and sporadic olivopontocerebellar atrophy. Additionally, there is a hereditary form of olivopontocerebellar atrophy that is not part of the multiple system atrophy spectrum.
WE MOVE (Worldwide Education and Awareness for Movement Disorders)
204 West 84th Street
New York, NY 10024
Parkinson's Disease Foundation, Inc.
New York, NY 10018
National Institute of Neurological Disorders and Stroke (NINDS)
P.O. Box 5801
Bethesda, MD 20824
Autonomic Dysfunction Center
Vanderbilt University Medical Center
Nashville, TN 37232-2195
National Dysautonomia Research Foundation
PO Box 301
Red Wing, MN 55066-0102
MUMS National Parent-to-Parent Network
150 Custer Court
Green Bay, WI 54301-1243
Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg, MD 20898-8126
Shy-Drager Syndrome/Multiple System Atrophy Support Group
P.O. Box 279
Coupland, TX 78615
PO Box 241956
Los Angeles, CA 90024
National Parkinson Foundation, Inc.
1501 NW 9th Ave/Bob Hope Road
Miami, FL 33136-1494
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This is an abstract of a report from the National Organization for Rare Disorders, Inc. ® (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html