National Organization for Rare Disorders, Inc.

It is possible that the main title of the report Lipodystrophy is not the name you expected.

Disorder Subdivisions

  • Total Lipodystrophy
  • Partial Lipodystrophy
  • Localized Lipodystrophy
  • Acquired Lipodystrophy
  • Acquired Partial Lipodystrophy
  • Barraquer-Simons Disease
  • Berardinelli-Seip Syndrome
  • Centrifugal Lipodystrophy
  • Cephalothoracic Lipodystrophy
  • Congenital Lipodystrophy
  • Hollaender-Simons Disease
  • Insulin Lipodystrophy
  • Koebberling-Dunnigan Syndrome
  • Lawrence-Seip Syndrome
  • Leprechaunism
  • Lipoatrophic Diabetes Mellitus
  • Membranous Lipodystrophy
  • Mesenteric Lipodystrophy
  • Nasu Lipodystrophy
  • Progressive Lipodystrophy
  • Seip Syndrome
  • Simons Syndrome
  • Smith Disease
  • Unilateral Partial Lipodystrophy
  • Whipple Disease

General Discussion

Lipodystrophies are a group of rare metabolic disorders which can be either inherited or acquired. They are characterized by abnormalities in fatty (adipose) tissue associated with total or partial loss of body fat, abnormalities of carbohydrate and lipid metabolism, severe resistance to naturally occurring and synthetic insulin, and immune system dysfunction. These disorders are differentiated by degrees of severity, and by areas or systems of the body affected. Lipodystrophies can also be associated with other disorders and various developmental abnormalities.


CLIMB (Children Living with Inherited Metabolic Diseases)
Climb Building
176 Nantwich Road
Crewe, Intl CW2 6BG
United Kingdom
Tel: +44 870 7700 325
Fax: +44 870 7700 327

March of Dimes Birth Defects Foundation
1275 Mamaroneck Avenue
White Plains, NY 10605
Tel: (914)997-4488
Fax: (914)997-4763
Tel: (888)663-4637

Arc (a national organization on mental retardation)
1010 Wayne Ave
Suite 650
Silver Spring, MD 20910
Tel: (301)565-3842
Fax: (301)565-3843
Tel: (800)433-5255
TDD: (817)277-0553

American Diabetes Association
Attn: National Call Center
1701 N. Beauregard Street
Alexandria, VA 22311
Tel: (703)549-1500
Fax: (703)549-6995
Tel: (800)342-2383

NIH/National Digestive Diseases Information Clearinghouse
2 Information Way
Bethesda, MD 20892-3570
Tel: (301)654-3810
Fax: (301)907-8906
Tel: (800)891-5389

MUMS National Parent-to-Parent Network
150 Custer Court
Green Bay, WI 54301-1243
Tel: (920)336-5333
Fax: (920)339-0995
Tel: (877)336-5333

Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg, MD 20898-8126
Tel: (301)251-4925
Fax: (301)251-4911
Tel: (888)205-2311
TDD: (888)205-3223

International Scleroderma Network
7455 France Ave So #266
Edina, MN 55435-4702
Tel: (952)583-5735
Tel: (800)564-7099

International Mesenteric Panniculitis Society

For a Complete Report

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ® (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see

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