Binswanger's Disease

National Organization for Rare Disorders, Inc.

Important
It is possible that the main title of the report Binswanger's Disease is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.

Synonyms

  • Binswanger's Encephalopathy
  • Multi-infarct Dementia, Binswanger's Type
  • Subcortical Dementia
  • Vascular Dementia, Binswanger's Type
  • Subcortical Ischemic Vascular Disease
  • Subcortical Arteriosclerotic Encephalopathy, SAE

Disorder Subdivisions

  • None

General Discussion

Binswanger's disease is a progressive neurological disorder characterized by atherosclerotic blood vessels supplying the white-matter and deep structures of the brain (basal ganglia and thalamus). Most patients experience progressive memory loss and deterioration of intellectual abilities (dementia), urinary urgency or incontinence, and an abnormally slow, shuffling, unsteady pattern of walking, usually over a 5-10 year period. Due to their vascular etiology, the symptoms and physical findings associated with Binswanger's disease may suddenly worsen due to stroke, stabilize and then improve for a brief time, but the patient's overall condition continues to progress as the blood vessels become increasingly obstructed.

Resources

National Association for Continence
PO Box 1019
Charleston, SC 29402
United States
Tel: (843)377-0900
Fax: (342)377-0905
Tel: (800)252-3337
Email: memberservices@nafc.org
Internet: http://www.nafc.org

Alzheimer's Association
225 North Michigan Avenue, Floor 17
Chicago, IL 60601-7633
USA
Tel: (312)335-8700
Fax: (866)699-1246
Tel: (800)272-3900
TDD: (312)335-5886
Email: info@alz.org
Internet: http://www.alz.org

Alzheimer's Disease Education and Referral Center
P.O. Box 8250
Silver Spring, MD 20907-8250
Tel: (301)495-3311
Fax: (301)495-3334
Tel: (800)438-4380
Email: adear@alzheimers.org
Internet: http://www.alzheimers.org

NIH/National Institute on Aging
PO Box 8057
Gaithersburg, MD 20892-8057
Tel: (301)496-1752
Tel: (800)222-2225
Internet: http://www.nih.gov/nia

National Institute of Neurological Disorders and Stroke (NINDS)
P.O. Box 5801
Bethesda, MD 20824
Tel: (301)496-5751
Fax: (301)402-2186
Tel: (800)352-9424
TDD: (301)468-5981
Email: me20t@nih.gov
Internet: http://www.ninds.nih.gov/

Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg, MD 20898-8126
Tel: (301)251-4925
Fax: (301)251-4911
Tel: (888)205-2311
TDD: (888)205-3223
Email: ordr@od.nih.gov
Internet: http://rarediseases.info.nih.gov/Default.aspx

For a Complete Report

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ® (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html

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