Churg Strauss Syndrome
National Organization for Rare Disorders, Inc.
It is possible that the main title of the report Churg Strauss Syndrome is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
- Allergic Angiitis and Granulomatosis
- Allergic Granulomatosis and Angiitis
- Allergic Granulomatosis
- Eosinophilic Granulomatous Vasculitis
- Churg-Strauss Vasculitis
Churg-Strauss Syndrome is a rare disorder that may affect multiple organ systems, particularly the lungs. The disorder is characterized by the formation and accumulation of an unusually large number of antibodies, abnormal clustering of certain white blood cells (eosinophilia), inflammation of blood vessels (vasculitis), and the development of inflammatory nodular lesions (granulomatosis).
Many individuals with Churg-Strauss Syndrome have a history of allergy. In addition, asthma and other associated lung (pulmonary) abnormalities (i.e., pulmonary infiltrates) often precede the development of the generalized (systemic) symptoms and findings seen in Churg-Strauss Syndrome by one or more years. Asthma, a chronic respiratory disorder, is characterized by inflammation and narrowing of the lungs' airways, causing difficulties breathing (dyspnea), coughing, the production of a high-pitched whistling sound while breathing (wheezing), and/or other symptoms and findings.
Nonspecific findings associated with Churg-Strauss Syndrome typically include flu-like symptoms, such as fever, a general feeling of weakness and fatigue (malaise), loss of appetite (anorexia), weight loss, and muscle pain (myalgia). Additional symptoms and findings may be variable, depending upon the specific organ systems involved. Without appropriate treatment, serious organ damage and potentially life-threatening complications may result.
Although the exact cause of Churg-Strauss Syndrome is unknown, many researchers indicate that abnormal immunologic and autoimmune factors play an important role.
P.O. Box 28660
Kansas City, MO 64188
American Lung Association
61 Broadway, 6th Floor
New York, NY 10006
NIH/National Heart, Lung and Blood Institute Information Center
P.O. Box 30105
Bethesda, MD 20824-0105
NIH/National Institute of Allergy and Infectious Diseases
6610 Rockledge Drive
Bethesda, MD 20892-6612
Vasculitis of the Central Nervous System
Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg, MD 20898-8126
Churg Strauss Syndrome Association
PO Box 671
Southampton, MA 01073-0671
PO Box 241956
Los Angeles, CA 90024
American Partnership for Eosinophilic Disorders
PO Box 29545
Atlanta, GA 30359
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This is an abstract of a report from the National Organization for Rare Disorders, Inc. ® (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html