Neutropenia, General

National Organization for Rare Disorders, Inc.

It is possible that the main title of the report Neutropenia, General is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.


  • Neutropenia, Autoimmune

Disorder Subdivisions

  • Neutropenia, Chronic Congenital
  • Neutropenia, Chronic Idiopathic
  • Neutropenia, Cyclic

General Discussion

Severe chronic neutropenia (SCN) is a rare blood disorder characterized by abnormally low levels of certain white blood cells (neutrophils) in the body (neutropenia). Neutrophils play an essential role in fighting bacterial infections by surrounding and destroying invading bacteria (phagocytosis). Symptoms associated with severe chronic neutropenia include recurring fevers, mouth sores (ulcers), and/or inflammation of the tissues that surround and support the teeth (periodontitis). Due to low levels of neutrophils, affected individuals may be more susceptible to recurring infections that, in some cases, may result in life-threatening complications. SCN may last for months or years and can affect both children and adults. Clinicians recognize four forms of the disorder: congenital, cyclical, idiopathic, and autoimmune neutropenia. The term idiopathic is used when severe chronic neutropenia occurs for unknown reasons.


National Neutropenia Network
PO Box 1693
Brighton, MI 48116
Tel: (810)229-5797

Severe Chronic Neutropenia International Registry
Plaza 600 Building
600 Stewart Street
Suite 1503
Seattle, WA 98101
Tel: (206)543-9749
Fax: (206)543-3668
Tel: (800)726-4463

NIH/National Heart, Lung and Blood Institute Information Center
P.O. Box 30105
Bethesda, MD 20824-0105
Tel: (301)592-8573
Fax: (301)251-1223

Neutropenia Support Association, Inc.
971 Corydon Avenue
P.O. Box 243
Manitoba, R3M 3S7
Tel: 2044898454
Tel: 8006638876

Severe Chronic Neutropenia International Registry Australia
2nd Floor Marian House
St. John of God Hospital
1002 Mair Street
Ballarat, 3350
Tel: 61-3-5333 4811
Fax: 61-3-5333 4813

MUMS National Parent-to-Parent Network
150 Custer Court
Green Bay, WI 54301-1243
Tel: (920)336-5333
Fax: (920)339-0995
Tel: (877)336-5333

Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg, MD 20898-8126
Tel: (301)251-4925
Fax: (301)251-4911
Tel: (888)205-2311
TDD: (888)205-3223

For a Complete Report

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ® (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see

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