Leukemia, Chronic Lymphocytic

National Organization for Rare Disorders, Inc.

Important
It is possible that the main title of the report Leukemia, Chronic Lymphocytic is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.

Synonyms

  • CLL

Disorder Subdivisions

  • None

General Discussion

Chronic Lymphocytic Leukemia is a malignant blood disorder in which there is an increased number of white blood cells formed in the lymphoid tissue. This uncontrolled buildup and enlargement of lymphoid tissue can occur in various sites of the body such as the lymph nodes, spleen, bone marrow, and lungs. There are many different forms of Leukemia which are all characterized by an overabundance of white blood cells. In Chronic Lymphocytic Leukemia the disease occurs in the lymphoid tissue.

The lymph vessels, which return fluids to the circulatory system, and the lymph nodes, which are a mass of tissue separated into compartments by connective tissue, make up the immune system. The lymph nodes serve as filters, removing foreign particles, tissue debris, and bacterial cells from the circulation. When this system is not working properly, the body's defenses cannot fight off foreign particles.

In the majority of cases, Chronic Lymphocytic Leukemia is the result of a rapid production of B lymphocyte cells (a short-lived type of white blood cell that is responsible for the production of vertebrate serum proteins that include antibodies). A small percentage of Chronic Lymphocytic Leukemia cases stem from the overproduction of T lymphocyte cells (a type of white blood cell that have a long life and are important in the resistance of disease).

Resources

Leukemia & Lymphoma Society
1311 Mamaroneck Avenue
Suite 310
White Plains, NY 10605
Tel: (914)949-5213
Fax: (914)949-6691
Tel: (800)955-4572
Email: infocenter@LLS.org
Internet: http://www.LLS.org

American Cancer Society, Inc.
1599 Clifton Road NE
Atlanta, GA 30329
USA
Tel: (404)320-3333
Tel: (800)227-2345
TDD: (866)228-4327
Internet: http://www.cancer.org

National Cancer Institute
6116 Executive Blvd, MSC 8322, Room 3036A
Bethesda, MD 20892-8322
USA
Tel: (301)435-3848
Tel: (800)422-6237
TDD: (800)332-8615
Internet: http://www.cancer.gov

OncoLink: The University of Pennsylvania Cancer Center Resource
3400 Spruce Street
2 Donner
Philadelphia, PA 19104-4283
USA
Tel: (215)349-5445
Fax: (215)349-5445
Email: editors@oncolink.upenn.edu
Internet: http://www.oncolink.upenn.edu

Children's Leukemia Research Association
585 Stewart Avenue, Suite 18
Garden City, NY 11530
Tel: (516)222-1944
Fax: (516)222-0457
Email: info@childrensleukemia.org
Internet: http://www.childrensleukemia.org

Cancer Research UK
PO Box 123
Lincoln's Inn Fields
London, Intl WC2A 3PX
United Kingdom
Tel: 020-7242 0200
Fax: 020-7269 3100
Internet: http://www.imperialcancer.co.uk

Rare Cancer Alliance
1649 North Pacana Way
Green Valley, AZ 85614
USA
Tel: (520)625-5495
Fax: (615)526-4921
Email: sharon.lane@rare-cancer.org
Internet: http://www.rare-cancer.org

MUMS National Parent-to-Parent Network
150 Custer Court
Green Bay, WI 54301-1243
USA
Tel: (920)336-5333
Fax: (920)339-0995
Tel: (877)336-5333
Email: mums@netnet.net
Internet: http://www.netnet.net/mums/

Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg, MD 20898-8126
Tel: (301)251-4925
Fax: (301)251-4911
Tel: (888)205-2311
TDD: (888)205-3223
Email: ordr@od.nih.gov
Internet: http://rarediseases.info.nih.gov/Default.aspx

Madisons Foundation
PO Box 241956
Los Angeles, CA 90024
Tel: (310)264-0826
Fax: (310)264-4766
Email: getinfo@madisonsfoundation.org
Internet: http://www.madisonsfoundation.org

Friends of Cancer Research
2231 Crystal Drive
Suite 200
Arlington, VA 22202
Tel: (703)302-1503
Fax: (703)302-1568
Email: info@focr.org
Internet: http://www.focr.org

UCSF Hemophilia Treatment Center
400 Parnassus Ave.
First Floor
San Francisco, CA 94143
Tel: (415)353-2986
Fax: (415)353-2600
Internet: http://www.ucsfhealth.org/adult/medical_services/blood/hemophilia/index.html

Cancer.Net
American Society of Clinical Oncology
2318 Mill Road
Suite 800
Alexandria, VA 22314
Tel: (571)483-1780
Fax: (571)366-9537
Tel: (888)651-3038
Email: contactus@cancer.net
Internet: http://www.cancer.net/patient

Wellness Community
919 18th Street N.W.
Suite 54
Washington, DC 20006
Tel: (202)659-9709
Fax: (202)659-9301
Tel: (888)793-9355
Email: help@thewellnesscommunity.org
Internet: http://www.thewellnesscommunity.org

Lance Armstrong Foundation
2201 E. Sixth Street
Austin, TX 78702
Tel: (512)236-8820
Fax: (512)236-8482
Tel: (877)236-8820
Email: media@livestrong.org
Internet: http://www.livestrong.org

For a Complete Report

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ® (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html

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