Antiphospholipid Syndrome

National Organization for Rare Disorders, Inc.

Important
It is possible that the main title of the report Antiphospholipid Syndrome is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.

Synonyms

  • APLS
  • APS
  • antiphospholipid antibody syndrome
  • Hughes syndrome
  • lupus anticoagulant syndrome
  • PAPS
  • primary antiphospholipid syndrome

Disorder Subdivisions

  • catastrophic antiphospholipid syndrome (Asherson’s syndrome)
  • CAPS

General Discussion

Antiphospholipid syndrome (APS) is a rare autoimmune disorder characterized by recurring blood clots (thromboses). Blood clots can form in any blood vessel of the body. The specific symptoms and severity of APS vary greatly from case to case depending upon the exact location of a blood clot and the organ system affected. APS may occur as an isolated disorder (primary antiphospholipid syndrome) or may occur along with another autoimmune disorder such as systemic lupus erythematosus (secondary antiphospholipid syndrome).

APS is characterized by the presence of antiphospholipid antibodies in the body. Antibodies are specialized proteins produced by the body's immune system to fight infection. In individuals with APS, certain antibodies mistakenly attack healthy tissue. In APS, antibodies mistakenly attack certain proteins that bind to phospholipids, which are fat molecules that are involved in the proper function of cell membranes. Phospholipids are found throughout the body. The reason these antibodies attack these proteins and the process by which they cause blood clots to form is not known.

Resources

American Autoimmune Related Diseases Association, Inc.
22100 Gratiot Avenue
Eastpointe, MI 48021
Tel: (586)776-3900
Fax: (586)776-3903
Tel: (800)598-4668
Email: aarda@aarda.org
Internet: http://www.aarda.org/

Lupus Foundation of America, Inc.
2000 L Street NW
Suite 710
Washington, DC 20036
USA
Tel: (202)349-1155
Fax: (202)349-1156
Tel: (800)558-0121
Email: info@lupus.org
Internet: http://www.lupus.org

National Stroke Association
9707 East Easter Lane
Englewood, CO 80112-3747
USA
Tel: (303)649-9299
Fax: (303)649-1328
Tel: (800)787-6537
Email: info@stroke.org
Internet: http://www.stroke.org

MUMS National Parent-to-Parent Network
150 Custer Court
Green Bay, WI 54301-1243
USA
Tel: (920)336-5333
Fax: (920)339-0995
Tel: (877)336-5333
Email: mums@netnet.net
Internet: http://www.netnet.net/mums/

Antiphospholipid Antibody Support Group
Marvin Nelson
4228 Deer Path Road
Apex, NC 27539-7282
Tel: (919)362-8977
Internet: http://www.egroups.com/group/aplsuk

Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg, MD 20898-8126
Tel: (301)251-4925
Fax: (301)251-4911
Tel: (888)205-2311
TDD: (888)205-3223
Email: ordr@od.nih.gov
Internet: http://rarediseases.info.nih.gov/Default.aspx

Madisons Foundation
PO Box 241956
Los Angeles, CA 90024
Tel: (310)264-0826
Fax: (310)264-4766
Email: getinfo@madisonsfoundation.org
Internet: http://www.madisonsfoundation.org

Autoimmune Information Network, Inc
PO Box 4121
Brick, NJ 08723
Tel: (732)664-9259
Email: autoimmunehelp@aol.com
Internet: http://www.aininc.org

APS Foundation of America, Inc
PO Box 801
624 North 10th Street
Suite 4
La Crosse, WI 54602-0801
Tel: (608)782-2626
Fax: (608)782-6569
Email: apsfa@apsfa.org
Internet: http://www.apsfa.org

National Alliance for Thrombosis and Thrombophilia
120 White Plains Road
Suite 100
Tarrytown, NY 10591
Tel: (914)220-5040
Tel: (877)466-2568
Email: info@stoptheclot.org
Internet: http://stoptheclot.org/index.htm

Hughes Syndrome Foundation
Louise Coote Lupus Unit
Gassiot House
St. Thomas' Hospital
London, SE1 7EH
England
Tel: 0207-188-8217
Email: hsf@btconnect.com
Internet: http://www.hughes-syndrome.org

For a Complete Report

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ® (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html

related physicians

related services

Bon Secours International| Sisters of Bon Secours USA| Bon Secours Health System

This information does not replace the advice of a doctor. Healthwise disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Privacy Policy. How this information was developed to help you make better health decisions.