Chromosomes

Chromosomes are cell structures that carry genetic material (DNA), or genes. They are a part of most types of cells in the body.

Humans have 46 chromosomes (23 pairs). Half of a person's chromosomes come from the mother and half from the father. One of the 23 pairs determines a person's gender. The sex chromosomes are called X and Y. For a child to be female, she must inherit an X chromosome from each parent (XX). For a child to be male, he must inherit an X chromosome from his mother and a Y chromosome from his father (XY).

The DNA of the chromosomes determines the features a person inherits from his or her parents, such as blood type, hair color, eye color, and other characteristics, including risks for developing certain diseases. Defects in chromosomes may cause changes in certain body processes or functions. These changes may be undetectable or may cause genetic diseases, such as hemophilia or Down syndrome. Defective genes can be passed from parents to children or can occur in a new mutation.

Last Updated: November 4, 2009

Author: Maria Essig

Medical Review: Kathleen Romito, MD - Family Medicine & Siobhan M. Dolan, MD, MPH - Reproductive Genetics

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