Islet cells and islet cell antibodies

Islet cells are located in the pancreas and make hormones including insulin, glucagon, somatomammotropin, and pancreatic polypeptide. In some people, the immune system produces islet cell antibodies, which attack and destroy the islet cells as though they were foreign substances; this can lead to serious health conditions, such as type 1 diabetes.

Last Updated: September 17, 2008

Author: Caroline Rea, RN, BS, MS

Medical Review: Caroline S. Rhoads, MD - Internal Medicine & Matthew I. Kim, MD - Endocrinology & Metabolism

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