Generic Name Brand Name
ifosfamide Ifex

How It Works

Ifosfamide is an intravenous (IV) medication usually given in a dose based on body surface area. The type and extent of a cancer determines the exact dose and schedule of administering this medication.

Why It Is Used

Ifosfamide interferes with the DNA of cancer cells. It is used to treat testicular cancer, cervical cancer, Ewing's sarcoma, and non-Hodgkin's lymphoma. It may also be used for lung or pancreatic cancer.

How Well It Works

Ifosfamide is an effective antitumor medication. However, the type and extent of a cancer determines how effectively this medication slows or stops the growth of cancer cells in the body.

Side Effects

Side effects of ifosfamide include:

  • Confusion.
  • Dizziness.
  • Nausea, vomiting, and loss of appetite.
  • Diarrhea or constipation.
  • Decreased white blood counts or platelet counts.

See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)

What To Think About

Ifosfamide should be administered only under the supervision of a medical oncologist or gynecological oncologist.

You may not be able to become pregnant or father a child after taking this medication. Discuss fertility with your doctor before starting treatment.

Ifosfamide can cause birth defects. Do not use this medication if you are pregnant or wish to become pregnant or father a child while you are taking it.

Do not use this medication if you have:

  • Liver disease.
  • Kidney disease.
  • Bone marrow depression.

Complete the new medication information form (PDF)(What is a PDF document?) to help you understand this medication.

Last Updated: January 26, 2009

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