Alloimmunization

Alloimmunization is a response by the body's immune system to donated blood or bone marrow or a transplanted organ. In alloimmunization, a person's body develops antibodies—proteins that attack and destroy foreign substances—that target the donated material.

A person receiving repeat blood transfusions may develop antibodies to the donor blood. Alloimmunization makes repeated transfusions more difficult.

Last Updated: December 9, 2008

Author: Debby Golonka, MPH

Medical Review: Anne C. Poinier, MD - Internal Medicine & Martin Steinberg, MD - Hematology

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