Anticholinergics and antispasmodics for urinary incontinence in men


Generic Name Brand Name
darifenacin hydrobromide Enablex
fesoterodine Toviaz
oxybutynin chloride Ditropan, Ditropan XL, Oxytrol
solifenacin succinate Vesicare
tolterodine tartrate Detrol, Detrol LA
trospium chloride Sanctura, Sanctura XR

How It Works

These medicines calm the nerves that control bladder muscles. They may prevent uncontrollable bladder contractions that force urine out of the bladder.

Why It Is Used

Antispasmodics and anticholinergics are used to control the symptoms of urge incontinence. These medicines may also be used to treat stress incontinence, especially if you have both stress and urge incontinence.

How Well It Works

These medicines can help men control urge incontinence. Typically, men who take these medicines can hold their urine for a longer time. And when they do have the urge to urinate, it is not as strong as it is without medicine.1

Side Effects

Side effects vary with some of these medicines and include:

  • Dry mouth.
  • Headache.
  • Decreased sweating, skin rash.
  • Nausea, constipation.
  • Eye problems.
  • Rapid heartbeat.
  • Skin rash.
  • Drowsiness, confusion.
  • Nervousness.
  • Urinary retention.

See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)

What To Think About

If you have the eye disease glaucoma, it is important for you to talk with your ophthalmologist before you start taking anticholinergics. People who have glaucoma may need to be watched more closely while they are taking anticholinergic medicines.

Some of these medicines may cause you to sweat less. In hot weather, this could lead to heat exhaustion. Ask your doctor whether you should be careful about being physically active in hot conditions.

Complete the new medication information form (PDF)(What is a PDF document?) to help you understand this medication.



  1. Nitti VW, Blaivas JG (2007). Urinary incontinence: Epidemiology, pathophysiology, evaluation, and management overview. In AJ Wein et al., eds., Campbell-Walsh Urology, 9th ed., vol. 3, pp. 2046–2078. Philadelphia: Saunders Elsevier.

Last Updated: July 21, 2008

related physicians

related services

Bon Secours International| Sisters of Bon Secours USA| Bon Secours Health System

This information does not replace the advice of a doctor. Healthwise disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Privacy Policy. How this information was developed to help you make better health decisions.

© 1995-2010 Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.